ASPIC

Sint Michielsgestel, Netherlands

14 - 20 June, 2024

See more informations here: https://event.eortc.org/mccr2025/

Sint Michielsgestel, Netherlands

14 - 20 June, 2024

See more informations here: https://event.eortc.org/mccr2025/

Brussels & online

20-21 November, 2024

See more informations here: https://www.europeancancer.org/summit.html

Researchers from the "Differentiation and Cancer" group at i3S, in collaboration with António Pombinho, from the "BioSciences Screening" platform, and Filipe Pereira, from Lund University, elucidated the role of the transcription factor HMGA1 in gastric cancer stem cells. The study, entitled "HMGA1 stimulates cancer stem-like features and sensitivity to monensin in gastric cancer," was recently published in the journal "Experimental Cell Research."

Investigadores do grupo “Diferenciação e Cancro” do i3S, em colaboração com António Pombinho, da plataforma “BioSciences Screening”, e Filipe Pereira, da Universidade de Lund, elucidaram o papel do fator de transcrição HMGA1 nas células estaminais de cancro gástrico. O estudo, intitulado “HMGA1 stimulates cancer stem-like features and sensitivity to monensin in gastric cancer”, foi recentemente publicado na revista “Experimental Cell Research”.

Essen, Germany

23 - 25 September 2025

See more informations here: https://www.eacr.org/conference/goodbyeflatbiology2025?utm_source=eacrnews&utm_medium=email&utm_campaign=GFB25&utm_content=

A recent study, led by Ricardo Marcos-Pinto and Ângela Fernandes, with Henrique Fernandes-Mendes as its first author, revealed associations between aberrant glycoprofiles and clinical variables. This study, conducted in the Immunology, Cancer & Glycomedicine group at i3S (led by Salomé Pinho), reveals an association between the levels of branched N-glycans in epithelial cells and factors such as age, smoking and polyp dimension, suggesting a link between these glycans and colorectal cancer progression.

Um estudo recente, liderado pelos investigadores Ricardo Marcos-Pinto e Ângela Fernandes, com a primeira autoria de Henrique Fernandes-Mendes, revelou associações entre perfis de glicosilação aberrantes e diversas variáveis clínicas.

O cancro da mama recetor de estrogénio positivo (ER+) é o subtipo mais diagnosticado em todo o mundo. O desenvolvimento de resistência endócrina associada ao tratamento destes tumores tem levado à implementação de novas estratégias como a combinação das terapias clássicas com novos agentes terapêuticos.

Authors and Affiliations:

Cristina Ferreira Almeida^1,2, Andreia Palmeira^3,4, Maria João Valente⁵, Georgina Correia-da-Silva^1,2, Anne Marie Vinggaard⁵, Maria Emília Sousa^3,4, Natércia Teixeira^1,2, Cristina Amaral^1,2

¹ UCIBIO, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, n° 228, 4050-313 Porto, Portugal