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Congresso CIMAGO - Novos horizontes na oncologia moderna: riscos emergentes e novos paradigmas na gestão integrada do Doente

Subunidade 3 - Pólo Ciências Saúde - FMUC - Coimbra, Portugal

 

29-30 January, 2026

 

See more information here: https://www.uc.pt/fmuc/cimago/eventos/congresso-cimago-29-e-30-janeiro-2026/

Congresso CIMAGO - Novos horizontes na oncologia moderna: riscos emergentes e novos paradigmas na gestão integrada do Doente

Subunidade 3 - Pólo Ciências Saúde - FMUC - Coimbra, Portugal

 

29-30 January, 2026

 

See more information here: https://www.uc.pt/fmuc/cimago/eventos/congresso-cimago-29-e-30-janeiro-2026/

EGFR and STAT3 as therapeutic targets in ETV1-positive prostate cancer

Researchers from the Cancer Genetics Group at IPO Porto, in collaboration with the School of Medicine and Biomedical Sciences at the University of Porto (ICBAS), have uncovered a key singaling pathway driving the aggressiveness of prostate tumors that overexpress ETV1. The team found that simultaneous activation of the EGFR and STAT3 signaling pathways fuels the malignant behavior of these cancers.

EGFR e STAT3 como alvos terapêuticos em carcinoma da próstata ETV1-positivo

Investigadores do Grupo de Oncogenética do IPO Porto, em colaboração com o Instituto de Ciências Biomédicas Abel Salazar da Univerisdade do Porto (ICBAS), identificaram uma via de sinalização que impulsiona a agressividade de carcinomas da próstata com sobre-expressão de ETV1. A equipa de investigação descobriu que a activação das vias EGFR e STAT3 promove o comportamento maligno destes carcinomas.

Absence of Telomerase Leads to Immune Response and Tumor Regression in Zebrafish

Lopes-Bastos et al. report that melanoma in zebrafish initiates without telomerase (or ALT) activation. However, in late progression, telomerase becomes essential for sustained tumor growth. Tumors that fail to re-activate telomerase slow down growth and even regress. This occurs due to tumor-autonomous (genomic instability) and non-tumor-autonomous (immune response) mechanisms.

Absence of Telomerase Leads to Immune Response and Tumor Regression in Zebrafish

Lopes-Bastos et al. report that melanoma in zebrafish initiates without telomerase (or ALT) activation. However, in late progression, telomerase becomes essential for sustained tumor growth. Tumors that fail to re-activate telomerase slow down growth and even regress. This occurs due to tumor-autonomous (genomic instability) and non-tumor-autonomous (immune response) mechanisms.

22º Congresso Nacional de Oncologia

Forum Braga - Braga

 

26-28 November, 2025

 

See more information here: https://cno.sponcologia.pt/2025/home.php?lg=1

22º Congresso Nacional de Oncologia

Forum Braga - Braga

 

26-28 November, 2025

 

See more information here: https://cno.sponcologia.pt/2025/home.php?lg=1

The EACR Conference on Cancer Metabolism

The EACR Conference on Cancer Metabolism