ASPIC

Metropolitan Hotel, Athens, Greece

9 - 11 October 2014

See more informations here: http://www.spandidos-publications.com/pages/conference

The New York Academy of Sciences, 7 World Trade Center, New York, United States

19 - 20 June 2014

See more informations here: http://www.nyas.org/Events/Detail.aspx?cid=ae4093af-7d17-4eb4-ac29-93118c62cb52

The New York Academy of Sciences, 7 World Trade Center, New York, United States

19 - 20 June 2014

See more informations here: http://www.nyas.org/Events/Detail.aspx?cid=ae4093af-7d17-4eb4-ac29-93118c62cb52

Kervansaray Bodrum Resort Hotel, Bodrum, Turkey

23 – 27 April, 2014 

See more informations here: http://www.cancerresearch2014.org/

Kervansaray Bodrum Resort Hotel, Bodrum, Turkey

23 – 27 April, 2014 

See more informations here: http://www.cancerresearch2014.org/

Eligible EACR members can now apply for an EACR Travel Fellowship at any time and hear the result within 10 working days. 
 

EACR's Travel Fellowships scheme, co-sponsored by the Association for International Cancer Research (AICR), offers researchers with less than four years postdoctoral experience (including PhD students) the opportunity to advance their research by visiting a centre of excellence in another country.

Eligible EACR members can now apply for an EACR Travel Fellowship at any time and hear the result within 10 working days. 
 

EACR's Travel Fellowships scheme, co-sponsored by the Association for International Cancer Research (AICR), offers researchers with less than four years postdoctoral experience (including PhD students) the opportunity to advance their research by visiting a centre of excellence in another country.

Gastric cancer is one of the most prevalent and fatal in the world, especially due to its invasive nature, and the capacity to metastasize at distance, frequently without symptoms. E-cadherin is one of the most important structural molecules in the stomach, and its expression in the gastric epithelia suppresses cancer development. Carriers of mutations in the gene encoding E-cadherin have high probability of developing hereditary diffuse gastric cancer. Strategies aiming to prevent the loss of E-cadherin expression enclose high therapeutic potential for gastric cancer.

O cancro de estômago é um dos mais prevalentes e mortais do mundo, principalmente devido às suas características invasivas, e capacidade de gerar metástases à distância, frequentemente sem sintomas. A Caderina-E é uma das moléculas mais importantes para a conservação da estrutura do estômago, e a sua expressão no epitélio gástrico suprime o desenvolvimento de cancro. Pessoas com mutações no gene que origina esta proteína têm uma probabilidade muito elevada de desenvolver cancro gástrico difuso hereditário.

Authors and Affiliations:

Inês M Gomes¹, Patrícia Arinto², Carlos Lopes^2,3, Cecília R Santos¹, Cláudio J Maia¹

¹- CICS-UBI- Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal

²- Institute of Biomedical Sciences Abel Salazar, University of Porto, Portugal

³- Department of Pathology, Centro Hospitalar do Porto, Porto, Portugal