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CDX2 homeoprotein regulates ST6GalNAc-I in intestinal metaplasia

This study, performed by a group of investigators at IPATIMUP and published in Laboratory Investigation, identified the marker of intestinal differentiation CDX2 as a modulator of the glycoproteome in intestinal metaplasia, a precursor lesion of gastric cancer characterized by a transdifferentiation of the gastric mucosa into intestinal mucosa. The study showed that CDX2 transcription factor directly regulates ST6GalNAc-I gene in intestinal metaplasia lesions.

O factor de transcrição CDX2 está envolvido na regulação da ST6GalNAc-I em metaplasia intestinal

Este estudo, realizado por um grupo de investigadores do IPATIMUP e publicado na revista Laboratory Investigation, identificou o marcador de diferenciação intestinal CDX2 como um modulador do glicoproteoma na metaplasia intestinal, uma lesão precursora de cancro gástrico que se caracteriza por uma transdiferenciação da mucosa gástrica em mucosa intestinal. O estudo mostrou que o factor de transcrição CDX2 regula directamente o gene da ST6GalNAc-I em lesões de metaplasia intestinal.

ESO - ESSO Advanced Course on Breast Cancer Surgery

ESO - ESSO Advanced Course on Breast Cancer Surgery

Conversation with the president of Memorial Sloan Kettering Cancer Center

Interview with Craig Thompson, MD, president and CEO of Memorial Sloan Kettering Cancer Center. From the series «Conversations with Giants in Medicina», at «The Journal of Clinical Investigation».

 

 

Conversation with the president of Memorial Sloan Kettering Cancer Center

Interview with Craig Thompson, MD, president and CEO of Memorial Sloan Kettering Cancer Center. From the series «Conversations with Giants in Medicina», at «The Journal of Clinical Investigation».

 

 

Department of Radiotherapy of Hospital de Santa Maria publishes results of eyelid carcinoma treatment with high-dose-rate brachytherapy

The Department of Radiotherapy of Hospital de Santa Maria has already published in Brachytherapy, the journal of American Society of Brachytherapy, the results of 17 cases of eyelid carcinomas treated with high-dose-rate interstitial brachytherapy. It is the publication with the largest number of basal cell carcinomas undergoing this type of treatment and the second largest in terms of total number of lesions, including basal and squamous cell carcinomas. With a median followup of 40 months, the local control rate was 94.1%, similar to that achieved with other treatments, including surgery.

Serviço de Radioterapia do Hospital de Santa Maria publica resultados do tratamento de carcinomas da pálpebra com braquiterapia de alta taxa de dose

O Serviço de Radioterapia do Hospital de Santa Maria publicou recentemente, na revista norte-americana Brachytherapy, o resultado de 17 casos de carcinomas da pálpebra tratados com braquiterapia intersticial de alta taxa de dose. Trata-se da publicação com maior número de basaliomas submetidos a este tipo de tratamento e a segunda maior em termos de número total de lesões, incluindo basaliomas e carcinomas pavimento-celulares. Com um followup mediano de 40 meses, a taxa de controlo local foi de 94,1%, semelhante à alcançada com outros tratamentos, incluindo a cirurgia.

15th ASEICA International Congress

Hotel NH Collection Sevilla, Sevilla, Spain

 

21-23 October, 2015

 

See more informations here: http://aseicacongress.es/

 

15th ASEICA International Congress

Hotel NH Collection Sevilla, Sevilla, Spain

 

21-23 October, 2015

 

See more informations here: http://aseicacongress.es/