Soft tissue sarcomas (STS) are a group of neoplasms, which, despite current therapeutic advances, still confer a poor outcome to half of the patients. In the present study, the expression and clinical-pathological significance of monocarboxylate transporters (MCTs), important proteins involved in cancer cells’ metabolic reprogramming, was evaluated in a series of 86 STS. Importantly, an association between MCT expression and poor prognostic variables was observed. Additionally, nuclear expression of MCT1 is described for the first time, being associated with good prognostic variables.
