Perspectives on emerging technologies, personalised medicine, and clinical research for cancer control in Latin America and the Caribbean

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Perspectives on emerging technologies, personalised medicine, and clinical research for cancer control in Latin America and the Caribbean

Friday, 05.11.2021

A investigação e a inovação em cancro na América Latina são limitadas devido a recursos académicos inadequados e a investigação de translação depende quase totalmente de financiamento público. A complexidade regulatória e os prazos de resposta excessivos colocam colocam em causa a melhoria potencial na participação em estudos internacionais. Tecnologias emergentes, inteligência artificial, big data e investigação em cancro representam uma oportunidade para enfrentar os desafios da saúde, otimizando as capacidades nacionais, num contexto de partilha das melhores práticas e da transferência de capacidades científicas e técnicas.

 

Authors and Affiliations:

Gustavo Werutsky 1, Carlos H Barrios 2, Andres F Cardona 3, André Albergaria 4, Alfonso Valencia 5, Carlos G Ferreira 6, Christian Rolfo 7, Evandro de Azambuja 8, Gabriel A Rabinovich 9, Georgina Sposetti 10, Oscar Arrieta 11, Rodrigo Dienstmann 12, Taiane F Rebelatto 13, Valeria Denninghoff 14, Veronica Aran 15, Eduardo Cazap 16

1 Latin American Cooperative Oncology Group, Porto Alegre, Brazil. 

2 Latin American Cooperative Oncology Group, Porto Alegre, Brazil; Oncology Department, Rio de Janeiro, Brazil.

3 Thoracic and Brain Tumor Unit, Clinical and Translational Oncology Group, Clínica del Country, Bogotá, Colombia; Foundation for Clinical and Applied Cancer Research (FICMAC), Bogotá, Colombia; Molecular Oncology and Biology Systems Research Group (Fox-G), Universidad el Bosque, Bogotá, Colombia.

4 Translational Research & Industry Partnerships Unit, Instituto de Inovação em Saúde (i3S), Porto, Portugal.

5 Institución Catalana de Investigación y Estudios Avanzados (ICREA) and Barcelona Supercomputing Center, Barcelona, Spain.

6 Instituto Oncoclinicas, Rio de Janeiro, Brazil.

7 Center for Thoracic Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

8 Medical Oncology Department, Institut Jules Bordet and l'Université Libre de Bruxelles, Brussels, Belgium.

9 Laboratory of Immunopathology, Institute of Biology and Experimental Medicine, and School of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires, Argentina.

10 Instituto de Investigaciones Clinicas Mar del Plata, Buenos Aires, Argentina; Un Ensayo para Mi, Buenos Aires, Argentina.

11 Department of Thoracic Oncology, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico.

12 Oncoclínicas Precision Medicine and Big Data Initiative, Rio de Janeiro, Brazil.

13 Latin American Cooperative Oncology Group, Porto Alegre, Brazil.

14 University of Buenos Aires - National Council for Scientific and Technical Research (CONICET), Buenos Aires, Argentina.

15 Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Brazil.

16 Latin American and Caribbean Society of Medical Oncology (SLACOM), Buenos Aires, Argentina.

 

Abstract:

Challenges of health systems in Latin America and the Caribbean include accessibility, inequity, segmentation, and poverty.  These  challenges  are  similar  in  different  countries  of  the  region  and  transcend  national  borders.  The  increasing  digital  transformation  of  health  care  holds  promise  of  more  precise  interventions,  improved  health  outcomes,  increased  efficiency,  and  ultimately  reduced  health-care  costs.  In  Latin  America  and  the  Caribbean,  the  adoption of digital health tools is in early stages and the quality of cancer registries, electronic health records, and structured  databases  are  problematic.  Cancer  research  and  innovation  in  the  region  are  limited  due  to  inadequate  academic  resources  and  translational  research  is  almost  fully  dependent  on  public  funding.  Regulatory  complexity  and  extended  timelines  jeopardise  the  potential  improvement  in  participation  in  international  studies.  Emerging  technologies, artificial intelligence, big data, and cancer research represent an opportunity to address the health-care challenges in Latin America and the Caribbean collectively, by optimising national capacities, sharing and comparing best practices, and transferring scientific and technical capabilities.

 

 
Journal: Lancet Oncology