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Breve revisão de inovações terapêuticas no tratamento do cancro do pulmão

A descoberta de genes cruciais e mal-expressos no cancro de pulmão permite um melhor entendimento do microambiente do tumor e dos biomarcadores que são uma impressão genética desse cancro. Esses biomarcadores fornecem um conhecimento relevante para iniciar o desenvolvimento de terapias direcionadas, superando os efeitos colaterais e o desenvolvimento de resistências associadas aos tratamentos convencionais. A terapia génica e os medicamentos baseados em RNAi são apontados como novas e promissoras abordagens para o tratamento do cancro de pulmão.

The Role of Diet Related SCFAs in CRC Metabolism and Survival

It was published a review article that covers the current knowledge on the transport of short chain fatty acids by colorectal cancer cells and their effects on colorectal cancer metabolism and survival. It is also adressed the impact of increasing short chain fatty acids production by manipulation of colon microbiota on the prevention and therapy of this disease.

The Role of Diet Related SCFAs in CRC Metabolism and Survival

It was published a review article that covers the current knowledge on the transport of short chain fatty acids by colorectal cancer cells and their effects on colorectal cancer metabolism and survival. It is also adressed the impact of increasing short chain fatty acids production by manipulation of colon microbiota on the prevention and therapy of this disease.

ECCO 2019 European Cancer Summit: «European Cancer Care: Across Borders»

Brussels, Belgium

 

12-14 September, 2019

 

See more informations here: https://www.eccosummit.eu/Summit

ECCO 2019 European Cancer Summit: «European Cancer Care: Across Borders»

Brussels, Belgium

 

12-14 September, 2019

 

See more informations here: https://www.eccosummit.eu/Summit

6th Annual ISCaM Meeting (International Society for Cancer Metabolism)

Bom Jesus do Monte, Braga, Portugal

 

17-19 October, 2019

 

See more informations here: https://www.iscams.org/meeting/iscam2019-6th-annual-meeting-braga

6th Annual ISCaM Meeting (International Society for Cancer Metabolism)

Bom Jesus do Monte, Braga, Portugal

 

17-19 October, 2019

 

See more informations here: https://www.iscams.org/meeting/iscam2019-6th-annual-meeting-braga

FEBS Advanced Lecture Course on Oncometabolism: From Conceptual Knowledge to Clinical Applications

Grande Hotel de Luso, Luso, Portugal

 

1-6 September, 2019

 

See more informations here: https://oncometabolism2019.febsevents.org

FEBS Advanced Lecture Course on Oncometabolism: From Conceptual Knowledge to Clinical Applications

Grande Hotel de Luso, Luso, Portugal

 

1-6 September, 2019

 

See more informations here: https://oncometabolism2019.febsevents.org

O-glycans truncation modulates gastric cancer cell signaling and transcription leading to a more aggressive phenotype

Neste estudo foi possível identificar o papel de alterações de glicosilação específicas no comportamento de células de cancro gástrico e como estas contribuem para a progressão tumoral levando a um pior prognóstico dos pacientes. Era já conhecido que as células malignas apresentam alterações de expressão de glicanos com estrutura truncada. Nomeadamente, pacientes com cancro gástrico revelam ter um aumento de glicanos truncados, como por exemplo o Sialyl-Tn.